dc.contributor.author | Chan, O | en_US |
dc.contributor.author | Havard, B | en_US |
dc.contributor.author | Morton, S | en_US |
dc.contributor.author | Pritchard, M | en_US |
dc.contributor.author | Maffulli, N | en_US |
dc.contributor.author | Crisp, T | en_US |
dc.contributor.author | Padhiar, N | en_US |
dc.contributor.author | Perry, JD | en_US |
dc.contributor.author | King, J | en_US |
dc.contributor.author | Morrissey, D | en_US |
dc.date.accessioned | 2017-10-03T09:13:05Z | |
dc.date.available | 2017-01-01 | en_US |
dc.date.issued | 2017-01 | en_US |
dc.date.submitted | 2017-09-22T13:30:31.831Z | |
dc.identifier.issn | 2240-4554 | en_US |
dc.identifier.uri | http://qmro.qmul.ac.uk/xmlui/handle/123456789/26423 | |
dc.description.abstract | BACKGROUND: The intra-tendinous tear is a new pathology that is defined as a discontinuity of fibres situated entirely within the tendon. Prolotherapy involves injecting an irritant, such as hyperosmolar dextrose, to stimulate a tissue healing response and ultimately reduce pain. METHODS: 43 consecutive patients diagnosed with an intra-tendinous tear were included (27 males: 16 females, mean (SD) age 41 (11.3). Patients were injected with 0.4ml-1.5ml (mean 0.8ml) of 50% dextrose and 0.5% marcaine mixed in a 1:1 ratio. A 4-6 week period of walking boot immobilisation was followed by progressive rehabilitation (6-8 weeks). Outcomes were assessed with a VISA-A questionnaire at baseline, 3 months and a mean 12.6 (7.0) months post-treatment. Ultrasound scans were conducted before treatment and 5.2 (2.3) weeks later to assess sonographic changes. RESULTS: 30 patients (70%) responded with VISA-A scores increasing by 31 (30.5) points after 3 months (f=0.62, p<0.05) and by 40 (29.3) points after 12.60 (7.0) months (f=0.87, p<0.05). After 5.2 (2.3) weeks, echogenicity was significantly reduced (p<0.05) and 27% of tears were no longer detectable. No significant differences were observed in remaining tears with respect to tear size, tendon thickness or neovascularisation. CONCLUSION: Treatment resulted in clinically significant improvements and controlled trials are warranted. LEVEL OF EVIDENCE: IV. | en_US |
dc.description.sponsorship | NIHR/HEE Senior Clinical Lecturer scheme.
National Institute for Health Research (NIHR) CAT SCL-2013-04-003. | en_US |
dc.format.extent | 78 - 87 | en_US |
dc.language | eng | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Muscles Ligaments Tendons J | en_US |
dc.subject | Achilles tendinopathy | en_US |
dc.subject | Achilles tendon | en_US |
dc.subject | dextrose | en_US |
dc.subject | intra-tendinous tear | en_US |
dc.subject | prolotherapy | en_US |
dc.subject | ultrasound | en_US |
dc.title | Outcomes of prolotherapy for intra-tendinous Achilles tears: a case series. | en_US |
dc.type | Article | |
dc.identifier.doi | 10.11138/mltj/2017.7.1.078 | en_US |
pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/28717615 | en_US |
pubs.issue | 1 | en_US |
pubs.notes | Not known | en_US |
pubs.publication-status | Published online | en_US |
pubs.volume | 7 | en_US |