Fibrinogen replacement in trauma haemorrhage.
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Scand J Trauma Resusc Emerg Med
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There is a growing interest in the role that fibrinogen plays in major haemorrhage. It has been known since 1995 that fibrinogen is one of the first coagulation proteins to fall to critically low levels during major blood loss , but the clinical relevance of this is only now being evaluated. Injury is the leading cause of death worldwide for patients aged 1-45 and accounts for 7,800 deaths in UK annually...
AuthorsCurry, N; Rourke, C; Davenport, R; Stanworth, S; Brohi, K
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