| dc.contributor.author | Zhang, Y | |
| dc.contributor.author | Ucuncu, M | |
| dc.contributor.author | Gambardella, A | |
| dc.contributor.author | Baibek, A | |
| dc.contributor.author | Geng, J | |
| dc.contributor.author | Zhang, S | |
| dc.contributor.author | Clavadetscher, J | |
| dc.contributor.author | Litzen, I | |
| dc.contributor.author | Bradley, M | |
| dc.contributor.author | Lilienkampf, A | |
| dc.date.accessioned | 2024-06-25T14:35:06Z | |
| dc.date.available | 2024-06-25T14:35:06Z | |
| dc.date.issued | 2020-12-16 | |
| dc.identifier.citation | TY - JOUR T1 - Bioorthogonal Swarming: In Situ Generation of Dendrimers AU - Zhang, Yichuan AU - Üçüncü, Muhammed AU - Gambardella, Alessia AU - Baibek, Assel AU - Geng, Jin AU - Zhang, Shuo AU - Clavadetscher, Jessica AU - Litzen, Inga AU - Bradley, Mark AU - Lilienkampf, Annamaria Y1 - 2020/12/30 PY - 2020 DA - 2020/12/30 N1 - doi: 10.1021/jacs.0c07869 DO - 10.1021/jacs.0c07869 T2 - Journal of the American Chemical Society JF - Journal of the American Chemical Society JO - J. Am. Chem. Soc. SP - 21615 EP - 21621 VL - 142 IS - 52 PB - American Chemical Society SN - 0002-7863 M3 - doi: 10.1021/jacs.0c07869 UR - https://doi.org/10.1021/jacs.0c07869 ER - | en_US |
| dc.identifier.issn | 0002-7863 | |
| dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/97690 | |
| dc.description.abstract | With the aid of bioorthogonal chemistry, we demonstrate the fabrication of synthetic dendrimers in situ around living cells. Using tetrazine dienophile and aminooxyl/hydrazide aldehyde chemistries, the density of functional groups on the dendrimers exponentially amplified intensities of fluorescent markers in antibody-targeted live cell imaging. This novel “swarming” approach highlights the power of bioorthogonal chemistry and provides a route to non-natural chemical structures on cells, paving the way for the generation of various artificial cellular nanostructures and scaffolds. | en_US |
| dc.format.extent | 21615 - 21621 | |
| dc.publisher | American Chemical Society | en_US |
| dc.relation.ispartof | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | |
| dc.rights | This document is the unedited Author’s version of a Submitted Work that was subsequently accepted for publication in Journal of the American Chemical Society , copyright © 2020 American Chemical Society after peer review. To access the final edited and published work see https://doi.org/10.1021/jacs.0c07869. | |
| dc.title | Bioorthogonal Swarming: In Situ Generation of Dendrimers | en_US |
| dc.type | Article | en_US |
| dc.identifier.doi | 10.1021/jacs.0c07869 | |
| pubs.author-url | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000605189000003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=612ae0d773dcbdba3046f6df545e9f6a | en_US |
| pubs.issue | 52 | en_US |
| pubs.notes | Not known | en_US |
| pubs.publication-status | Published | en_US |
| pubs.volume | 142 | en_US |
| rioxxterms.funder | Default funder | en_US |
| rioxxterms.identifier.project | Default project | en_US |
| qmul.funder | Adding Another Dimension – Arrays of 3D Bio-Responsive Materials::European Research Council | en_US |
