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Abstract P6-10-05: Mutations in the RNA Splicing Factor SF3B1 drive endocrine therapy resistance and confer a targetable replication stress response defect through PARP inhibition

dc.contributor.authorBland, Pen_US
dc.contributor.authorSaville, Hen_US
dc.contributor.authorRead, Aen_US
dc.contributor.authorWai, Pen_US
dc.contributor.authorMuirhead, Gen_US
dc.contributor.authorCurnow, Len_US
dc.contributor.authorNieminuszczy, Jen_US
dc.contributor.authorRavindran, Nen_US
dc.contributor.authorJohn, Men_US
dc.contributor.authorHedayat, Sen_US
dc.contributor.authorBarker, Hen_US
dc.contributor.authorWright, Jen_US
dc.contributor.authorYu, Len_US
dc.contributor.authorMavrommati, Ien_US
dc.contributor.authorPeck, Ben_US
dc.contributor.authorAllen, Men_US
dc.contributor.authorGazinska, Pen_US
dc.contributor.authorPemberton, Hen_US
dc.contributor.authorGulati, Aen_US
dc.contributor.authorNash, Sen_US
dc.contributor.authorNoor, Fen_US
dc.contributor.authorGuppy, Nen_US
dc.contributor.authorRoxanis, Ien_US
dc.contributor.authorBarlow, Sen_US
dc.contributor.authorKalirai, Hen_US
dc.contributor.authorCoupland, Sen_US
dc.contributor.authorBroderick, Ren_US
dc.contributor.authorAlsafadi, Sen_US
dc.contributor.authorHouy, Aen_US
dc.contributor.authorStern, M-Hen_US
dc.contributor.authorPettit, Sen_US
dc.contributor.authorChoudhary, Jen_US
dc.contributor.authorHaider, Sen_US
dc.contributor.authorNiedzwiedz, Wen_US
dc.contributor.authorLord, Cen_US
dc.contributor.authorNatrajan, Ren_US
dc.date.accessioned2024-01-03T11:39:30Z
dc.date.issued2023-03-01en_US
dc.identifier.issn0008-5472en_US
dc.identifier.urihttps://qmro.qmul.ac.uk/xmlui/handle/123456789/93316
dc.descriptionMeeting Abstracten_US
dc.format.extentp6-10-05-p6-10-05 - ?en_US
dc.language.isoenen_US
dc.publisherAmerican Association for Cancer Research (AACR)en_US
dc.relation.ispartofCancer Researchen_US
dc.subjectCanceren_US
dc.subjectGeneticsen_US
dc.subjectBiotechnologyen_US
dc.subjectHuman Genomeen_US
dc.subjectBreast Canceren_US
dc.subject5 Development of treatments and therapeutic interventionsen_US
dc.subject5.1 Pharmaceuticalsen_US
dc.subject2 Aetiologyen_US
dc.subject2.1 Biological and endogenous factorsen_US
dc.subject4 Detection, screening and diagnosisen_US
dc.subject4.1 Discovery and preclinical testing of markers and technologiesen_US
dc.subjectCanceren_US
dc.subject3 Good Health and Well Beingen_US
dc.titleAbstract P6-10-05: Mutations in the RNA Splicing Factor SF3B1 drive endocrine therapy resistance and confer a targetable replication stress response defect through PARP inhibitionen_US
dc.typeArticle
dc.rights.holder©2023 American Association for Cancer Research
dc.identifier.doi10.1158/1538-7445.sabcs22-p6-10-05en_US
pubs.issue5_Supplementen_US
pubs.notesNot knownen_US
pubs.volume83en_US
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US


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