dc.contributor.author | Shivakumar, N | en_US |
dc.contributor.author | Kelly, P | en_US |
dc.date.accessioned | 2023-11-17T13:01:51Z | |
dc.date.issued | 2024-01-01 | en_US |
dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/92047 | |
dc.description.abstract | PURPOSE OF REVIEW: Children with linear growth faltering refractory to nutritional management show evidence of environmental enteropathy, which may compromise nutrient availability. Protein could be particularly affected, due to the possibility of sub-optimal digestibility and/or increase in requirement for immune response. This increase in protein requirement along with poor intake could potentially lead to increased breakdown of body protein sources and in turn a depleted protein state. The present review focuses on protein status in children at risk of linear growth faltering and environmental enteropathy. One pig study is also presented. RECENT FINDINGS: There is consistent evidence of low circulating essential and conditionally essential amino acids, in children. One study showed no difference in protein synthesis/breakdown, and fat free mass (FFM) in children at risk of linear growth faltering and environmental enteropathy. Weanling pigs exposed to nutrient deprivation showed a decrease in plasma albumin, with a slower rate of weight and length accretion, and a lower FFM. SUMMARY: These findings emphasize the need for improving intake of high-quality protein in children living in regions with a high prevalence of environmental enteropathy, with careful studies of the effect on growth rate and protein status. | en_US |
dc.format.extent | 55 - 60 | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Curr Opin Clin Nutr Metab Care | en_US |
dc.title | Protein status in relation to linear growth faltering and environmental enteropathy. | en_US |
dc.type | Article | |
dc.identifier.doi | 10.1097/MCO.0000000000000989 | en_US |
pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/37922120 | en_US |
pubs.issue | 1 | en_US |
pubs.notes | Not known | en_US |
pubs.publication-status | Published | en_US |
pubs.volume | 27 | en_US |