dc.contributor.author | Armstrong, P | en_US |
dc.contributor.author | kirkby, N | en_US |
dc.date.accessioned | 2023-10-03T10:54:18Z | |
dc.date.available | 2023-09-20 | en_US |
dc.identifier.issn | 1524-4636 | en_US |
dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/91107 | |
dc.description.abstract | Prostacyclin is a fundamental signaling pathway traditionally associated with the cardiovascular system and protection against thrombosis but which also has regulatory functions in fibrosis, proliferation, and immunity. Prevailing dogma states that prostacyclin is principally derived from vascular endothelium, although it is known that other cells can also synthesize it. However, the role of nonendothelial sources in prostacyclin production has not been systematically evaluated resulting in an underappreciation of their importance relative to better characterized endothelial sources... | |
dc.publisher | American Heart Association | en_US |
dc.relation.ispartof | Arteriosclerosis, Thrombosis, and Vascular Biology | en_US |
dc.rights | This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited. | |
dc.title | Widening the prostacyclin paradigm: tissue fibroblasts are a critical site of production and 2 anti-thrombotic protection | en_US |
dc.type | Article | |
dc.rights.holder | © 2023 The Authors. Arteriosclerosis, Thrombosis, and Vascular Biology is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. | |
pubs.notes | Not known | en_US |
pubs.publication-status | Accepted | en_US |
dcterms.dateAccepted | 2023-09-20 | en_US |