Asthma prescribing according to Arg16Gly beta-2 genotype: a randomized trial in adolescents
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Publisher
Journal
European Respiratory Journal
ISSN
0903-1936
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The A allele of rs1042713 (Arg16 amino acid) in the β2-adrenoreceptor is associated with poor response to long-acting β2-agonist (LABA) in young people with asthma. Our aim was to assess whether the prescribing of second-line controller with LABA or a leukotriene receptor antagonist according to Arg16Gly genotype would result in improvements in Pediatric Asthma-Related Quality of Life Questionnaire (PAQLQ).