Show simple item record

A cancer-associated, genome protective programme engaging PKCε.

dc.contributor.authorParker, PJ
dc.contributor.authorLockwood, N
dc.contributor.authorDavis, K
dc.contributor.authorKelly, JR
dc.contributor.authorSoliman, TN
dc.contributor.authorPardo, AL
dc.contributor.authorMarshall, JJT
dc.contributor.authorRedmond, JM
dc.contributor.authorVitale, M
dc.contributor.authorSilvia Martini
dc.date.accessioned2020-11-18T10:02:26Z
dc.date.available2020-10-02
dc.date.available2020-11-18T10:02:26Z
dc.date.issued2020-12
dc.identifier.citationPeter J. Parker, Nicola Lockwood, Khalil Davis, Joanna R. Kelly, Tanya N. Soliman, Ainara Lopez Pardo, Jacqueline J.T. Marshall, Joanna M. Redmond, Marco Vitale, Silvia Martini, A cancer-associated, genome protective programme engaging PKCε, Advances in Biological Regulation, Volume 78, 2020, 100759, ISSN 2212-4926, https://doi.org/10.1016/j.jbior.2020.100759.en_US
dc.identifier.urihttps://qmro.qmul.ac.uk/xmlui/handle/123456789/68410
dc.description.abstractAssociated with their roles as targets for tumour promoters, there has been a long-standing interest in how members of the protein kinase C (PKC) family act to modulate cell growth and division. This has generated a great deal of observational data, but has for the most part not afforded clear mechanistic insights into the control mechanisms at play. Here, we review the roles of PKCε in protecting transformed cells from non-disjunction. In this particular cell cycle context, there is a growing understanding of the pathways involved, affording biomarker and interventional insights and opportunities.en_US
dc.format.extent100759 - ?
dc.languageeng
dc.relation.ispartofAdvances in Biological Regulation
dc.rightsOpen access article under the CC BY license
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectAurora Ben_US
dc.subjectCell cycleen_US
dc.subjectNon-disjunctionen_US
dc.subjectPKCeen_US
dc.titleA cancer-associated, genome protective programme engaging PKCε.en_US
dc.typeArticleen_US
dc.rights.holder© 2020 The Authors.
dc.identifier.doi10.1016/j.jbior.2020.100759
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/33039823en_US
pubs.notesNot knownen_US
pubs.publication-statusPublisheden_US
pubs.volume78en_US
dcterms.dateAccepted2020-10-02
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US


Files in this item

Thumbnail
Name:
Soliman_cancer-associated-geno ...
Size:
967.1Kb
Format:
application/
Description:
Published version
View/Open

This item appears in the following Collection(s)

Show simple item record

Open access article under the CC BY license
Except where otherwise noted, this item's license is described as Open access article under the CC BY license