Genetics of Pituitary Tumours.
| dc.contributor.author | Loughrey, PB | |
| dc.contributor.author | Korbonits, M | |
| dc.date.accessioned | 2020-04-28T12:58:05Z | |
| dc.date.available | 2020-04-28T12:58:05Z | |
| dc.date.issued | 2019-10-07 | |
| dc.identifier.citation | Loughrey P.B., Korbonits M. (2019) Genetics of Pituitary Tumours. In: Igaz P., Patócs A. (eds) Genetics of Endocrine Diseases and Syndromes. Experientia Supplementum, vol 111. Springer, Cham | en_US |
| dc.identifier.isbn | 978-3-030-25904-4 | |
| dc.identifier.issn | 1664-431X | |
| dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/63790 | |
| dc.description.abstract | Pituitary tumours are relatively common in the general population. Most often they occur sporadically, with somatic mutations accounting for a significant minority of somatotroph and corticotroph adenomas. Pituitary tumours can also develop secondary to germline mutations as part of a complex syndrome or as familial isolated pituitary adenomas. Tumours occurring in a familial setting may present at a younger age and can behave more aggressively with resistance to treatment. This chapter will focus on the genetics and molecular pathogenesis of pituitary tumours. | en_US |
| dc.format.extent | 171 - 211 | |
| dc.language | eng | |
| dc.language.iso | en | en_US |
| dc.publisher | Springer Nature Switzerland AG | en_US |
| dc.relation.ispartof | Exp Suppl | |
| dc.subject | AIP | en_US |
| dc.subject | Carney complex | en_US |
| dc.subject | DICER1 | en_US |
| dc.subject | FIPA | en_US |
| dc.subject | Genetics | en_US |
| dc.subject | MEN1 | en_US |
| dc.subject | MEN4 | en_US |
| dc.subject | McCune-Albright syndrome | en_US |
| dc.subject | Pituitary tumour | en_US |
| dc.subject | X-LAG | en_US |
| dc.subject | ACTH-Secreting Pituitary Adenoma | en_US |
| dc.subject | Germ-Line Mutation | en_US |
| dc.subject | Growth Hormone-Secreting Pituitary Adenoma | en_US |
| dc.subject | Humans | en_US |
| dc.subject | Pituitary Neoplasms | en_US |
| dc.title | Genetics of Pituitary Tumours. | en_US |
| dc.type | Book chapter | en_US |
| dc.rights.holder | Springer Nature Switzerland AG 2019 | |
| dc.identifier.doi | 10.1007/978-3-030-25905-1_10 | |
| pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/31588533 | en_US |
| pubs.notes | Not known | en_US |
| pubs.publication-status | Published | en_US |
| pubs.volume | 111 | en_US |
| rioxxterms.funder | Default funder | en_US |
| rioxxterms.identifier.project | Default project | en_US |
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Centre for Endocrinology [560]
