Genetics of Pituitary Tumours.
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Accepted version
Embargoed until: 5555-01-01
Embargoed until: 5555-01-01
Volume
111
Pagination
171 - 211
Publisher
ISBN-13
978-3-030-25904-4
DOI
10.1007/978-3-030-25905-1_10
Journal
Exp Suppl
ISSN
1664-431X
Metadata
Show full item recordAbstract
Pituitary tumours are relatively common in the general population. Most often they occur sporadically, with somatic mutations accounting for a significant minority of somatotroph and corticotroph adenomas. Pituitary tumours can also develop secondary to germline mutations as part of a complex syndrome or as familial isolated pituitary adenomas. Tumours occurring in a familial setting may present at a younger age and can behave more aggressively with resistance to treatment. This chapter will focus on the genetics and molecular pathogenesis of pituitary tumours.
Authors
Loughrey, PB; Korbonits, MCollections
- Centre for Endocrinology [559]
Language
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