Centre for Clinical Trials & Methodology: Recent submissions
Now showing items 181-200 of 263
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Health insurance enrollment strategies during the Affordable Care Act (ACA): a scoping review on what worked and for whom.
(BMC part of Springer Nature, 2021-07-12)BACKGROUND: The Affordable Care Act (ACA) provided an opportunity for millions of people in the U.S. to get coverage from the publicly funded Medicaid program or private insurance from the newly established marketplace. ... -
ESCP Safe Anastomosis ProGramme in CoLorectal SurgEry (EAGLE): Study protocol for an international cluster randomised trial of a quality improvement intervention to reduce anastomotic leak following right colectomy.
(Wiley, 2021-07-13)AIM: Cohort data suggest that anastomotic leak occurs after 8% of right colectomies causing significant morbidity and mortality. Patient selection, intra-operative factors, and technical variation all contribute to risk ... -
Using the right words to address racial disparities in COVID-19
(Elsevier BV, 2020-08) -
Determinants of adolescent substance use in Africa: a systematic review and meta-analysis protocol
(Springer Science and Business Media LLC, 2021-12)<jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Adolescent substance use continues to be a growing major public health concern in Africa. Recent studies infer an overall estimated ... -
Progression from external pilot to definitive randomised controlled trial: a methodological review of progression criteria reporting.
(BMJ, 2021-06-28)OBJECTIVES: Prespecified progression criteria can inform the decision to progress from an external randomised pilot trial to a definitive randomised controlled trial. We assessed the characteristics of progression criteria ... -
EQ-5D-5L Health-State Values for the Mexican Population.
(2021-06-26)OBJECTIVE: To generate a value set for the Mexican adult general population to support and facilitate the inclusion of quality-adjusted life years (QALYs) into the health technology assessment process of the Mexican ... -
Pilot and feasibility studies for pragmatic trials have unique considerations and areas of uncertainty.
(2021-07-03)BACKGROUND AND OBJECTIVE: Feasibility studies are increasingly being used to support the development of, and investigate uncertainties around, future large-scale trials. The future trial can be designed with either a ... -
Cohort profile update: The Yorkshire Health Study.
(2021-02-11) -
Transparency of informed consent in pilot and feasibility studies is inadequate: a single-center quality assurance study.
(BioMed Central, 2021-04-16)BACKGROUND: Pilot and feasibility studies (PAFS) often have complex objectives aimed at assessing feasibility of conducting a larger study. These may not be clear to participants in pilot studies. METHODS: Here, we aimed ... -
Methods and results used in the development of a consensus-driven extension to the Consolidated Standards of Reporting Trials (CONSORT) statement for trials conducted using cohorts and routinely collected data (CONSORT-ROUTINE).
(BMJ Publishing Group, 2021-04-29)OBJECTIVES: Randomised controlled trials conducted using cohorts and routinely collected data, including registries, electronic health records and administrative databases, are increasingly used in healthcare intervention ... -
The Early Youth Engagement in first episode psychosis (EYE-2) study: pragmatic cluster randomised controlled trial of implementation, effectiveness and cost-effectiveness of a team-based motivational engagement intervention to improve engagement.
(2021-04-12)BACKGROUND: Early Intervention in Psychosis (EIP) services improve health outcomes for young people with psychosis in the medium-long term, but 25% of young people disengage in the first 12 months with costs to their mental ... -
Key concepts in clinical epidemiology: Stepped wedge trials
(Elsevier, 2021-04-20) -
Stillbirth maternity care measurement and associated factors in population-based surveys: EN-INDEPTH study.
(BMC part of Springer Nature, 2021-02-08)BACKGROUND: Household surveys remain important sources of maternal and child health data, but until now, standard surveys such as Demographic and Health Surveys (DHS) have not collected information on maternity care for ... -
Gestational age data completeness, quality and validity in population-based surveys: EN-INDEPTH study.
(BMC part of Springer Nature, 2021-02-08)BACKGROUND: Preterm birth (gestational age (GA) <37 weeks) is the leading cause of child mortality worldwide. However, GA is rarely assessed in population-based surveys, the major data source in low/middle-income countries. ... -
Stillbirth outcome capture and classification in population-based surveys: EN-INDEPTH study.
(BMC part of Springer Nature, 2021-02-08)BACKGROUND: Household surveys remain important sources of stillbirth data, but omission and misclassification are common. Classifying adverse pregnancy outcomes as stillbirths requires accurate reporting of vital status ... -
Neonatal and child mortality data in retrospective population-based surveys compared with prospective demographic surveillance: EN-INDEPTH study.
(BMC part of Springer Nature, 2021-02-08)BACKGROUND: Global mortality estimates remain heavily dependent on household surveys in low- and middle-income countries, where most under-five deaths occur. Few studies have assessed the accuracy of mortality data or ...