Centre for Clinical Trials & Methodology: Recent submissions
Now showing items 161-180 of 263
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Illuminating black holes. Part 2: Vortices, soap stars, and bubble galaxies
(IOP Publishing, 2017-05-01)The addition of soap to vortexing water produces bubble structures around the vortices' 'throats' that resemble galaxies of stars. Such soap-bubble models can be used to suggest the prediction that, at the heart of spiral ... -
Synergism and rules from combination of Baicalin, Jasminoidin and Desoxycholic acid in refined Qing Kai Ling for treat ischemic stroke mice model.
(Public Library of Science, 2012-09-26)Refined Qing-Kai-Ling (QKL), a modified Chinese medicine, consists of three main ingredients (Baicalin, Jasminoidin and Desoxycholic acid), plays a synergistic effect on the treatment of the acute stage of ischemic stroke. ... -
Barriers and enablers to routine register data collection for newborns and mothers: EN-BIRTH multi-country validation study.
(BioMed Central, 2021-03-26)BACKGROUND: Policymakers need regular high-quality coverage data on care around the time of birth to accelerate progress for ending preventable maternal and newborn deaths and stillbirths. With increasing facility births, ... -
Antibiotic use for inpatient newborn care with suspected infection: EN-BIRTH multi-country validation study.
(BioMed Central, 2021-03-26)BACKGROUND: An estimated 30 million neonates require inpatient care annually, many with life-threatening infections. Appropriate antibiotic management is crucial, yet there is no routine measurement of coverage. The Every ... -
Immediate newborn care and breastfeeding: EN-BIRTH multi-country validation study.
(BioMed Central, 2021-03-26)BACKGROUND: Immediate newborn care (INC) practices, notably early initiation of breastfeeding (EIBF), are fundamental for newborn health. However, coverage tracking currently relies on household survey data in many settings. ... -
Survey of women's report for 33 maternal and newborn indicators: EN-BIRTH multi-country validation study.
(2021-03-26)BACKGROUND: Population-based household surveys, notably the Demographic and Health Surveys (DHS) and Multiple Indicator Cluster Surveys (MICS), remain the main source of maternal and newborn health data for many low- and ... -
Counting on birth registration: mixed-methods research in two EN-BIRTH study hospitals in Tanzania.
(2021-03-26)BACKGROUND: Birth registration marks a child's right to identity and is the first step to establishing citizenship and access to services. At the population level, birth registration data can inform effective programming ... -
Birthweight measurement processes and perceived value: qualitative research in one EN-BIRTH study hospital in Tanzania.
(2021-03-26)BACKGROUND: Globally an estimated 20.5 million liveborn babies are low birthweight (LBW) each year, weighing less than 2500 g. LBW babies have increased risk of mortality even beyond the neonatal period, with an ongoing ... -
Kangaroo mother care: EN-BIRTH multi-country validation study.
(2021-03-26)BACKGROUND: Kangaroo mother care (KMC) reduces mortality among stable neonates ≤2000 g. Lack of data tracking coverage and quality of KMC in both surveys and routine information systems impedes scale-up. This paper evaluates ... -
Neonatal resuscitation: EN-BIRTH multi-country validation study.
(BioMed Central, 2021-03-26)BACKGROUND: Annually, 14 million newborns require stimulation to initiate breathing at birth and 6 million require bag-mask-ventilation (BMV). Many countries have invested in facility-based neonatal resuscitation equipment ... -
Stillbirths including intrapartum timing: EN-BIRTH multi-country validation study.
(BioMed Central, 2021-03-26)BACKGROUND: An estimated >2 million babies stillborn around the world each year lack visibility. Low- and middle-income countries carry 84% of the burden yet have the least data. Most births are now in facilities, hence ... -
Uterotonics for prevention of postpartum haemorrhage: EN-BIRTH multi-country validation study.
(BioMed Central, 2021-03-26)BACKGROUND: Postpartum haemorrhage (PPH) is a leading cause of preventable maternal mortality worldwide. The World Health Organization (WHO) recommends uterotonic administration for every woman after birth to prevent PPH. ... -
Cluster randomised trials of individual-level interventions were at high risk of bias.
(2021-06-28)OBJECTIVES: To describe the prevalence of risks of bias in cluster-randomised trials of individual-level interventions, according to the Cochrane Risk of Bias tool. STUDY DESIGN AND SETTING: Review undertaken in duplicate ...