RSS 1.0Institute of Population Health Sciences
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Robit regression in Stata
(2023-09-01)Logistic and probit models are the most popular regression models for binary outcomes. A simple robust alternative is the robit model, which replaces the underlying normal distribution in the probit model with a Student’s ... -
Intravenous immunoglobulin treatment in childhood encephalitis (IgNiTE): a randomised controlled trial.
(2023-11-09)OBJECTIVE: To investigate whether intravenous immunoglobulin (IVIG) improves neurological outcomes in children with encephalitis when administered early in the illness. DESIGN: Phase 3b multicentre, double-blind, randomised ... -
Accelerated versus standard epirubicin followed by cyclophosphamide, methotrexate, and fluorouracil or capecitabine as adjuvant therapy for breast cancer (UK TACT2; CRUK/05/19): quality of life results from a multicentre, phase 3, open-label, randomised, controlled trial.
(2023-11-02)BACKGROUND: Adjuvant chemotherapy for patients with early breast cancer improves outcomes but its toxicity affects patients' quality of life (QOL). The UK TACT2 trial investigated whether accelerated epirubicin improves ... -
Stakeholder views on the barriers and facilitators of psychosocial interventions to address reduction in aggressive challenging behaviour in adults with intellectual disabilities.
(NIHR Open Research, 2023)BACKGROUND: Success of psychosocial interventions in reducing aggressive challenging behaviour is likely to be related not only to mechanistic aspects, but also to therapeutic and system factors. The study aims to examine ... -
Complex interventions for aggressive challenging behaviour in adults with intellectual disability: A rapid realist review informed by multiple populations
(PLoS, 2023)Approximately 10% of people with intellectual disability display aggressive challenging behaviour, usually due to unmet needs. There are a variety of interventions available, yet a scarcity of understanding about what ... -
IMP2ART: development of a multi-level programme theory integrating the COM-B model and the iPARIHS framework, to enhance implementation of supported self-management of asthma in primary care.
(2023-11-13)BACKGROUND: Supported asthma self-management, incorporating an asthma action plan and annual clinical review, has been recommended by UK/global guidelines for over three decades. However, implementation remains poor, as ... -
Multimorbidity as chronic crisis: 'Living on' with multiple long-term health conditions in a socially disadvantaged London borough.
(2023-11-13)Contemporary health services are primarily designed around single diseases. People with multimorbidity (multiple long-term health conditions) often become burdened by accumulated treatments. Through multimodal fieldwork ... -
Implementing psychological interventions delivered by respiratory professionals for people with COPD. A stakeholder interview study.
(2023-10-25)Implementing psychological interventions in healthcare services requires an understanding of the organisational context. We conducted an interview study with UK National Health Service stakeholders to understand the barriers ... -
Reply: Tuberculosis screening in migrants to the EU/EEA and UK.
(2023-11)Tuberculosis incidence estimates from countries of origin alone are often insufficient to predict TB prevalence among migrants https://bit.ly/3PDc35g -
Art Therapy as a treatment for adults with a learning disability who are experiencing mental distress: A configurative systematic review with narrative synthesis
This systematic review with narrative synthesis aimed to identify the forms of art therapy practice, types of studies conducted, outcomes reported, and experiences described in the literature for people with learning ... -
Adapt and Adjust: Doing UK-Based Ethnographic Fieldwork During the Covid-19 Pandemic.
(2022)The Covid-19 pandemic has required many anthropologists to do fieldwork differently: research that would otherwise have been done face-to-face has been shifted online, sometimes very quickly. When doing research with people ... -
Novel class of photochromic molecules exhibiting photo-switching in the solid state.
(2023)Photo-switching compounds are widely used as super-resolution imaging agents, anti-counterfeiting dyes, and molecules that are able to control drug-receptor interactions. However, advancement of this field has been limited ... -
Rapid detection of major Gram-positive pathogens in ocular specimens using a novel fluorescent vancomycin-based probe
(2022-09-01)Bacterial infections of the eye are significant causes of morbidity that can lead to permanent visual loss without rapid and adequate treatment, with Gram-positive bacteria causing the majority of ocular infections. Here ... -
Synthesis of a water-soluble protoporphyrin polymer and its research on photodynamic inactivation of drug-resistant bacteria and cancer cells
(2022-12-30)Protoporphyrin IX (PPIX) is a photosensitizer in the photodynamic therapy. However, its aqueous insolubility is always a challenge for extensive applications. In this work, a water-soluble derivative of PPIX were synthesized ...
