Centre for Clinical Trials & Methodology
A tutorial on sample size calculation for multiple-period cluster randomized parallel, cross-over and stepped-wedge trials using the Shiny CRT Calculator. (2020-02-22)It has long been recognized that sample size calculations for cluster randomized trials require consideration of the correlation between multiple observations within the same cluster. When measurements are taken at anything ...
Cluster over individual randomization: are study design choices appropriately justified? Review of a random sample of trials (SAGE Publications, 2020-05-05)
(Wiley Online, 2020-02)What is already known about this topic? Lateral cerebral ventriculomegaly in the fetus associates with increased risk of neuropsychiatric disorders in childhood and adulthood. Vitamin D deficiency has been posited as a ...
(BioMed Central, 2020-01-15)Background: The aim was to estimate the prevalence of frailty and relative contribution of physical/balance, nutritive, cognitive and sensory frailty to important adverse health states (falls, physical activity levels, ...