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Facilitators and barriers to linkage to HIV care and treatment among female sex workers in a community-based HIV prevention intervention in Tanzania: A qualitative study.
(2019)
BACKGROUND: HIV-infected female sex workers (FSWs) have poor linkage to HIV care in sub-Sahara Africa. METHODS: We conducted 21 participatory group discussions (PGDs) to explore factors influencing linkage to HIV care among ...
Different temperature thresholds for antipyretic intervention in critically ill children with fever due to infection: the FEVER feasibility RCT.
(2019-02)
BACKGROUND: Fever accelerates host immune system control of pathogens but at a high metabolic cost. The optimal approach to fever management and the optimal temperature thresholds used for treatment in critically ill ...
Self-reported long-term needs after stroke.
(2011-05)
BACKGROUND AND PURPOSE: Development of interventions to manage patients with stroke after discharge from the hospital requires estimates of need. This study estimates the prevalence of self-reported need in community-dwelling ...
Patient engagement with research: European population register study.
(2015-12)
BACKGROUND: Lay involvement in implementation of research evidence into practice may include using research findings to guide individual care, as well as involvement in research processes and policy development. Little is ...
Long term probability of detection of HIV-1 drug resistance after starting antiretroviral therapy in routine clinical practice.
(2005-03-25)
BACKGROUND: Little is known about the long term risk of development of HIV-1 drug resistance for patients starting antiretroviral therapy (ART) with three or four drug regimens in routine clinical practice. METHODS: We ...
Margin status and survival outcomes after breast cancer conservation surgery: prospectively registered systematic review and meta-analysis.
(2022-09-21)
OBJECTIVE: To determine if margin involvement is associated with distant recurrence and to determine the required margin to minimise both local recurrence and distant recurrence in early stage invasive breast cancer. DESIGN: ...
Targeting protein biotinylation enhances tuberculosis chemotherapy.
(2018-04-25)
Successful drug treatment for tuberculosis (TB) depends on the unique contributions of its component drugs. Drug resistance poses a threat to the efficacy of individual drugs and the regimens to which they contribute. ...
Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial.
(2019-03-09)
BACKGROUND: High blood pressure is common in acute stroke and is a predictor of poor outcome; however, large trials of lowering blood pressure have given variable results, and the management of high blood pressure in ...