Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis.
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Autoimmunity to neuronal proteins occurs in several neurological syndromes, where cellular and humoral responses are directed to surface as well as intracellular antigens. Similar to myelin autoimmunity, pathogenic immune response to neuroaxonal components such as neurofilaments may contribute to neurodegeneration in multiple sclerosis.
AuthorsPuentes, F; van der Star, BJ; Victor, M; Kipp, M; Beyer, C; Peferoen-Baert, R; Ummenthum, K; Pryce, G; Gerritsen, W; Huizinga, R; Reijerkerk, A; van der Valk, P; Baker, D; Amor, S
- Immune Systems