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dc.contributor.authorMcEvoy, MDen_US
dc.contributor.authorGupta, Ren_US
dc.contributor.authorKoepke, EJen_US
dc.contributor.authorFeldheiser, Aen_US
dc.contributor.authorMichard, Fen_US
dc.contributor.authorLevett, Den_US
dc.contributor.authorThacker, JKMen_US
dc.contributor.authorHamilton, Men_US
dc.contributor.authorGrocott, MPWen_US
dc.contributor.authorMythen, MGen_US
dc.contributor.authorMiller, TEen_US
dc.contributor.authorEdwards, MRen_US
dc.contributor.authorPOQI-3 workgroupen_US
dc.contributor.authorPOQI chairsen_US
dc.contributor.authorMiller, TEen_US
dc.contributor.authorMythen, MGen_US
dc.contributor.authorGrocott, MPen_US
dc.contributor.authorEdwards, MRen_US
dc.contributor.authorPhysiology groupen_US
dc.contributor.authorPreoperative blood pressure groupen_US
dc.contributor.authorIntraoperative blood pressure groupen_US
dc.contributor.authorPostoperative blood pressure groupen_US
dc.date.accessioned2019-08-06T08:49:23Z
dc.date.available2019-01-03en_US
dc.date.issued2019-05en_US
dc.identifier.urihttps://qmro.qmul.ac.uk/xmlui/handle/123456789/58819
dc.description.abstractBACKGROUND: Postoperative hypotension and hypertension are frequent events associated with increased risk of adverse outcomes. However, proper assessment and management is often poorly understood. As a part of the PeriOperative Quality Improvement (POQI) 3 workgroup meeting, we developed a consensus document addressing this topic. The target population includes adult, non-cardiac surgical patients in the postoperative phase outside of the ICU. METHODS: A modified Delphi technique was used, evaluating papers published in MEDLINE examining postoperative blood pressure monitoring, management, and outcomes. Practice recommendations were developed in line with National Institute for Health and Care Excellence guidelines. RESULTS: Consensus recommendations were that (i) there is evidence of harm associated with postoperative systolic arterial pressure <90 mm Hg; (ii) for patients with preoperative hypertension, the threshold at which harm occurs may be higher than a systolic arterial pressure of 90 mm Hg; (iii) there is insufficient evidence to precisely define the level of postoperative hypertension above which harm will occur; (iv) a greater frequency of postoperative blood pressure measurement is likely to identify risk of harm and clinical deterioration earlier; and (v) there is evidence of harm from withholding beta-blockers, angiotensin receptor blockers, and angiotensin-converting enzyme inhibitors in the postoperative period. CONCLUSIONS: Despite evidence of associations with postoperative hypotension or hypertension with worse postoperative outcome, further research is needed to define the optimal levels at which intervention is beneficial, to identify the best methods and timing of postoperative blood pressure measurement, and to refine the management of long-term antihypertensive treatment in the postoperative phase.en_US
dc.format.extent575 - 586en_US
dc.languageengen_US
dc.language.isoenen_US
dc.relation.ispartofBr J Anaesthen_US
dc.subjectantihypertensive drugsen_US
dc.subjectblood pressureen_US
dc.subjecthypertensionen_US
dc.subjecthypotensionen_US
dc.subjectmyocardial infarctionen_US
dc.subjectoutcomesen_US
dc.subjectpostoperativeen_US
dc.subjectsurgeryen_US
dc.subjectAntihypertensive Agentsen_US
dc.subjectBlood Pressureen_US
dc.subjectBlood Pressure Determinationen_US
dc.subjectDelphi Techniqueen_US
dc.subjectElective Surgical Proceduresen_US
dc.subjectEvidence-Based Medicineen_US
dc.subjectHumansen_US
dc.subjectHypertensionen_US
dc.subjectHypotensionen_US
dc.subjectPerioperative Careen_US
dc.subjectPostoperative Complicationsen_US
dc.subjectPrognosisen_US
dc.subjectRisk Assessmenten_US
dc.titlePerioperative Quality Initiative consensus statement on postoperative blood pressure, risk and outcomes for elective surgery.en_US
dc.typeArticle
dc.rights.holder© 2019 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.
dc.identifier.doi10.1016/j.bja.2019.01.019en_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/30916008en_US
pubs.issue5en_US
pubs.notes6 monthsen_US
pubs.publication-statusPublisheden_US
pubs.volume122en_US
dcterms.dateAccepted2019-01-03en_US
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US
qmul.funderParasympathetic modulation of perioperative myocardial injury.::Royal College Of Anaesthetists/ British Journal of Anaesthesiaen_US
qmul.funderParasympathetic modulation of perioperative myocardial injury.::Royal College Of Anaesthetists/ British Journal of Anaesthesiaen_US


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