Browsing Theses by Subject "Pancreatic cancer"
Now showing items 1-8 of 8
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Desmoplastic stromal cells modulate tumour cell behaviour in pancreatic cancer
(Queen Mary University of London, 2013-01)Pancreatic ductal adenocarcinoma (PDAC) is characterised by an intense desmoplastic stromal response that can comprise 60 to 80% of tumour volume and has been implicated to be a factor in pr ... -
Ferromagnetically filled carbon nanotubes: Radial structures and tuning of magnetic properties through new synthesis methods.
(Queen Mary University of London, 2013)Multiwall carbon nanotubes filled with continuous single-crystals of the ferromagnetic phase -Fe were produced with two new synthesis methods: the boundary layer chemical vapour synthesis and the perturbed vapour chemical ... -
Molecular Characterization of Perineural Invasion in Pancreatic Ductal Adenocarcinoma: Proteomic Analysis and In Vitro Modelling.
(Queen Mary University of London, 2013-09)Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer, and the 5th most common cause of cancer death in the UK. One of the peculiarities of this malignancy is its ability to invade nerves, a ... -
Molecular Mechanisms of Lymphatic Invasion in Pancreatic Ductal Adenocarcinoma.
(Queen Mary University of London, 2012-05)Pancreatic Ductal Adenocarcinoma (PDAC) is one of the five leading causes of cancer-related deaths in the West, and this, largely, is due to metastatic disease. In order to better understand PDAC metastatic spread and ... -
Non-Regenerative Benefits of Adult Bone Marrow Derived Stem Cells for Myocardial Protection
(Queen Mary University of London, 2013)Ischaemic heart disease is the most common cause of mortality in the western hemisphere and it is rapidly becoming the leading cause of death globally. Moreover, therapeutic interventions by cardiologists and cardiac surgeons ... -
The role of epithelial cell-derived tumour necrosis Factor Alpha in pancreatic carcinogenesis
(Queen Mary University of London, 2012-03)Activating mutations of the kras proto-oncogene are found in more than 90 % of human pancreatic ductal adenocarcinoma (PDAC) and can result in increased activity of the NF-κB pathway, leading to constitutive production ... -
SOCIAL INFORMATION USE IN SOCIAL INSECTS
(Queen Mary University of London, 07/11/2014)Social learning plays a valuable role in the lives of many animal taxa, sometimes allowing individuals to bypass the costs of personal exploration. The ubiquity of this behaviour may arise from the fact that learning from ... -
Studying the role of integrin αVβ6 in pancreatic cancer
(Queen Mary University of London, 2013-01)Pancreatic cancer is often referred to as the “silent killer“ due to the asymptomatic nature of the disease in the early stages and the extremely poor prognosis overall. The average one-year survival rate for PDAC patients ...