Centre for Genomics and Child Health: Recent submissions
Now showing items 461-480 of 836
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Where Do Inhaled Fossil Fuel-derived Particles Go?
(2017-10-01) -
Still failing to tackle air pollution.
(2017-08-09) -
Extrafine Versus Fine Inhaled Corticosteroids in Relation to Asthma Control: A Systematic Review and Meta-Analysis of Observational Real-Life Studies.
(2018-05)BACKGROUND: The particle size of inhaled corticosteroids (ICSs) may affect airway drug deposition and effectiveness. OBJECTIVE: To compare the effectiveness of extrafine ICSs (mass median aerodynamic diameter, <2 μm) versus ... -
Diesel, children and respiratory disease.
(2018)Air pollution generated in urban areas is a global public health burden since half of the world's population live in either cities, megacities or periurban areas. Its direct effects include initiating and exacerbating ... -
Early Initiation and Exclusivity of Breastfeeding in Rural Zimbabwe: Impact of a Breastfeeding Intervention Delivered by Village Health Workers.
(2019-04)Background: Suboptimal breastfeeding contributes to >800,000 global child deaths annually. Optimal breastfeeding includes early initiation (EI) and exclusive breastfeeding (EBF) for the first 6 mo. Objectives: We tested ... -
Primary prevention of ROP and the oxygen saturation targeting trials.
(2019-10)Reducing the burden of visual morbidity from retinopathy of prematurity (ROP) begins with primary prevention, and improvements in neonatal care with a positive impact on ROP are possible in all settings. Strategies range ... -
Authors' Reply.
(2018-01) -
Children With Noncritical Infections Have Increased Intestinal Permeability, Endotoxemia and Altered Innate Immune Responses
(Wolters Kluwer Health Inc., 2019-07)BACKGROUND: Children with critical illness have increased intestinal permeability and a period of immunoparalysis, mediated by elevated circulating endotoxin. Whether children with less severe infections have similar ... -
Sustained protein synthesis and reduced eEF2K levels in TAp73-\- mice brain: a possible compensatory mechanism
(Taylor & Francis, 2018-12-04)The transcription factor p73 is a member of the p53 family, of which the transactivation domain containing isoform (TAp73) plays key roles in brain development and neuronal stem cells. TAp73 also facilitates homoeostasis ... -
Current Understanding of Innate Immune Cell Dysfunction in Childhood Undernutrition.
(2019)Undernutrition affects millions of children in low- and middle-income countries (LMIC) and underlies almost half of all deaths among children under 5 years old. The growth deficits that characterize childhood undernutrition ... -
Theory-based self-management intervention to improve adolescents' asthma control: a cluster randomised controlled trial protocol.
(2019-04-23)INTRODUCTION: Asthma-related morbidity and mortality in the UK is higher than elsewhere in Europe. Although the reasons for this are largely unclear, one explanation could be a higher prevalence of poorly controlled asthma ... -
Developing patient and public involvement and engagement (PPIE) in diabetes research: a local approach
(2019-05-01)Copyright © 2019 John Wiley & Sons, Ltd. In this paper, we describe our understanding of what patient and public involvement and engagement (PPIE) in diabetes research actually means to our local Diabetes Research Group ... -
Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years.
(2018-11-19)Importance: This work quantifies the fatal burden of dementia associated with Alzheimer disease in individuals with Down syndrome (DS). Objective: To explore the association of dementia associated with Alzheimer disease ... -
The role of microRNAs in newborn brain development and hypoxic ischaemic encephalopathy.
(Elsevier, 2019-02-01)Neonates can develop hypoxic-ischaemic encephalopathy (HIE) due to lack of blood supply or oxygen, resulting in a major cause of death and disability among term newborns. However, current definitive treatment of therapeutic ...