Centre for Immunobiology: Recent submissions
Now showing items 341-360 of 1121
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HIV-1 Vpr accessory protein interacts with REAF and mitigates its associated anti-viral activity
(2019-03-01)Meeting Report -
Increased spontaneous CCL2 (MCP-1) and CCL5 (RANTES) secretion in vitro in LADA compared to type 1 diabetes and type 2 diabetes: Action LADA 14.
(2020-12-23)AIMS: Immune-mediated type 1 diabetes (T1D) in adulthood and latent autoimmune diabetes in adults (LADA) share similar pathological mechanisms but differ clinically in disease progression. The aim of this study was to ... -
Deep Sequencing of B Cell Receptor Repertoires From COVID-19 Patients Reveals Strong Convergent Immune Signatures.
(2020)Deep sequencing of B cell receptor (BCR) heavy chains from a cohort of 31 COVID-19 patients from the UK reveals a stereotypical naive immune response to SARS-CoV-2 which is consistent across patients. Clonal expansion of ... -
Comparable Vδ2 Cell Functional Characteristics in Virally Suppressed People Living with HIV and Uninfected Individuals.
(MDPI, 2020-12-01)Crosstalk between innate and adaptive pathways is a critical component to developing an effective, lasting immune response. Among natural effector cells, innate-like γδ T cells promote immunity by facilitating communication ... -
Editorial Overview: Endogenous Retroviruses in Development and Disease
(MDPI AG, 2020-12-16)Editorial. As guest editors, we are pleased to present this Special Issue on endogenous retroviruses (ERVs) and their impact on mammalian development and disease [...] -
Clinical manifestations, prevalence, risk factors, outcomes, transmission, diagnosis and treatment of COVID-19 in pregnancy and postpartum: a living systematic review protocol.
(BMJ, 2020-12-02)INTRODUCTION: Rapid, robust and continually updated evidence synthesis is required to inform management of COVID-19 in pregnant and postpartum women and to keep pace with the emerging evidence during the pandemic. METHODS ... -
Starvation and Its Effects on the Gut.
(Oxford University Press, 2020-12-03)There is growing awareness that intestinal dysfunction determines the clinical outcomes of situations as diverse as undernourished children in urban tropical slums and undernourished surgical patients in intensive care ... -
Vitamin D3 replacement enhances antigen-specific immunity in older adults
(Oxford University Press., 2020-11-25) -
Reply
(2020-07-25)To the Editor: Refers to: Gary K. Soffer, Randy Horwitz, Andrew Weil Nonpharmacologic therapeutic possibilities for immunosenescence Journal of Allergy and Clinical Immunology, Volume 146, Issue 4, October 2020, Pages 922 -
Distinct Contribution of DNA Methylation and Histone Acetylation to the Genomic Occupancy of Transcription Factors
(2019-06-13)Abstract Epigenetic modifications on chromatin play important roles in regulating gene expression. While chromatin states are often governed by multi-layered structure, how individual pathways contribute to gene expression ... -
Activation of the B cell receptor leads to increased membrane proximity of the Igα cytoplasmic domain.
(2013)Binding of antigen to the B cell receptor (BCR) induces conformational changes in BCR's cytoplasmic domains that are concomitant with phosphorylation of the immunoreceptor tyrosine-based activation motifs (ITAMs). Recently, ...