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The A150V polymorphism of genotype 3 hepatitis C virus polymerase inhibits interferon alfa by suppressing protein kinase R activation.
(2020-11-25)
BACKGROUND AND AIMS: Despite recent advances in antiviral therapy for HCV, a proportion of patients with genotype 3 (G3) HCV infection do not respond to current all oral treatment regimens [1,2]. Genomic analyses have ...
Hepatosplenic schistosomiasis in Zambian adults is characterized by increased liver stiffness: A nested case-control study.
(2020-07-28)
Cirrhosis commonly complicates portal hypertension worldwide but in Zambia hepatosplenic schistosomiasis (HSS) dominates as the cause of portal hypertension. We need easier and non-invasive ways to assess HSS. Transient ...