Browsing Centre for Immunobiology by Author "O'Donnell, S"
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Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease
Reisdorf, WC; Xie, Q; Zeng, X; Xie, W; Rajpal, N; Hoang, B; Burgert, ME; Kumar, V; Hurle, MR; Rajpal, DK (2019-04-19)Epoxyeicosatrienoic acids (EETs) are signaling lipids produced by cytochrome P450 epoxygenation of arachidonic acid, which are metabolized by EPHX2 (epoxide hydrolase 2, alias soluble epoxide hydrolase or sEH). EETs have ...