Browsing Centre for Immunobiology by Author "IBD Pharmacogenetics Study Group"
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Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease.
Walker, GJ; Harrison, JW; Heap, GA; Voskuil, MD; Andersen, V; Anderson, CA; Ananthakrishnan, AN; Barrett, JC; Beaugerie, L; Bewshea, CM (American Medical Association, 2019-02-26)Importance: Use of thiopurines may be limited by myelosuppression. TPMT pharmacogenetic testing identifies only 25% of at-risk patients of European ancestry. Among patients of East Asian ancestry, NUDT15 variants are ...