Browsing Centre for Endocrinology by Subject "Growth Hormone-Secreting Pituitary Adenoma"
Now showing items 1-5 of 5
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Fatal Carney Complex in Siblings Due to De Novo Large Gene Deletion.
(2017-11-01)Context: Carney complex (CNC) is a rare multiple neoplasia syndrome involving cardiac, endocrine, neural, and cutaneous tumors and a variety of pigmented skin lesions. CNC can be inherited as an autosomal dominant trait, ... -
The genetic background of acromegaly.
(2017-02)Acromegaly is caused by a somatotropinoma in the vast majority of the cases. These are monoclonal tumors that can occur sporadically or rarely in a familial setting. In the last few years, novel familial syndromes have ... -
Genetics of Pituitary Tumours.
(Springer Nature Switzerland AG, 2019-10-07)Pituitary tumours are relatively common in the general population. Most often they occur sporadically, with somatic mutations accounting for a significant minority of somatotroph and corticotroph adenomas. Pituitary tumours ... -
Novel AIP mutation in exon 6 causing acromegaly in a German family.
(2023-08)The most frequent genetic alteration of familial isolated growth hormone producing pituitary neuroendocrine tumors is a germline mutation of the aryl hydrocarbon receptor-interacting protein (AIP) gene. Various AIP mutations ... -
Patient-reported outcomes of parenteral somatostatin analogue injections in 195 patients with acromegaly.
(2016-03)BACKGROUND: Long-acting somatostatin analogues delivered parenterally are the most widely used medical treatment in acromegaly. This patient-reported outcomes survey was designed to assess the impact of chronic injections ...