Now showing items 1-6 of 6

    • AIP and the somatostatin system in pituitary tumours. 

      Ibáñez-Costa, A; Korbonits, M (2017-12)
      Classic somatostatin analogues aimed at somatostatin receptor type 2, such as octreotide and lanreotide, represent the mainstay of medical treatment for acromegaly. These agents have the potential to decrease hormone ...
    • Cantú syndrome with coexisting familial pituitary adenoma. 

      Marques, P; Spencer, R; Morrison, PJ; Carr, IM; Dang, MN; Bonthron, DT; Hunter, S; Korbonits, M (2018-03)
      CONTEXT: Pseudoacromegaly describes conditions with an acromegaly related physical appearance without abnormalities in the growth hormone (GH) axis. Acromegaloid facies, together with hypertrichosis, are typical manifestations ...
    • Fatal Carney Complex in Siblings Due to De Novo Large Gene Deletion. 

      Stelmachowska-Banas, M; Zgliczynski, W; Tutka, P; Carney, JA; Korbonits, M (2017-11-01)
      Context: Carney complex (CNC) is a rare multiple neoplasia syndrome involving cardiac, endocrine, neural, and cutaneous tumors and a variety of pigmented skin lesions. CNC can be inherited as an autosomal dominant trait, ...
    • From pituitary adenoma to pituitary neuroendocrine tumor (PitNET): an International Pituitary Pathology Club proposal. 

      Asa, SL; Casar-Borota, O; Chanson, P; Delgrange, E; Earls, P; Ezzat, S; Grossman, A; Ikeda, H; Inoshita, N; Karavitaki, N (2017-04)
      The classification of neoplasms of adenohypophysial cells is misleading because of the simplistic distinction between adenoma and carcinoma, based solely on metastatic spread and the poor reproducibility and predictive ...
    • Genetic Aspects of Pituitary Adenomas. 

      Marques, P; Korbonits, M (2017-06)
      Although most of pituitary adenomas are benign, they may cause significant burden to patients. Sporadic adenomas represent the vast majority of the cases, where recognized somatic mutations (eg, GNAS or USP8), as well as ...
    • Systematic Investigation of Expression of G2/M Transition Genes Reveals CDC25 Alteration in Nonfunctioning Pituitary Adenomas. 

      Butz, H; Németh, K; Czenke, D; Likó, I; Czirják, S; Zivkovic, V; Baghy, K; Korbonits, M; Kovalszky, I; Igaz, P (2017-07)
      Dysregulation of G1/S checkpoint of cell cycle has been reported in pituitary adenomas. In addition, our previous finding showing that deregulation of Wee1 kinase by microRNAs together with other studies demonstrating ...