Browsing Centre for Endocrinology by Author "Taylor, AE"

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    • Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma. 

      Chortis, V; Taylor, AE; Doig, CL; Walsh, MD; Meimaridou, E; Jenkinson, C; Rodriguez-Blanco, G; Ronchi, CL; Jafri, A; Metherell, LA (2018-08-01)
      Adrenocortical carcinoma (ACC) is an aggressive malignancy with poor response to chemotherapy. In this study, we evaluated a potential new treatment target for ACC, focusing on the mitochondrial reduced form of NAD phosphate ...

    • Novel methods in adrenal research: a metabolomics approach. 

      Papathomas, TG; Sun, N; Chortis, V; Taylor, AE; Arlt, W; Richter, S; Eisenhofer, G; Ruiz-Babot, G; Guasti, L; Walch, AK (Springer Link, 2019-02-06)
      Metabolic alterations have implications in a spectrum of tissue functions and disease. Aided by novel molecular biological and computational tools, our understanding of physiological and pathological processes underpinning ...