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Launch of mini-reviews in hot topics.
(2018-07)
Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis
(Springer Berlin Heidelberg, 2018-08-14)
Purpose:
Pre-clinical animal studies precede the majority of clinical trials. While the clinical sepsis definitions and recommended treatments are regularly updated, a systematic review of pre-clinical models of sepsis ...
Metabolic Syndrome in Cushing's Syndrome Patients.
(2018)
Cushing's syndrome (CS), including visceral obesity, dyslipidemia, hypertension and diabetes among its many manifestations, is "a model" of metabolic syndrome. Glucocorticoid (GC) excess, through a combination of effects ...
A critical role for the ATP-sensitive potassium channel subunit KIR6.1 in the control of cerebral blood flow.
(2018-06-04)
KIR6.1 (KCNJ8) is a subunit of ATP sensitive potassium channel (KATP) that plays an important role in the control of peripheral vascular tone and is highly expressed in brain contractile cells (vascular smooth muscle cells ...