Browsing Centre for Tumour Biology by Subject "Receptor, ErbB-2"

Now showing items 1-2 of 2

    • CADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity. 

      Vallath, S; Sage, EK; Kolluri, KK; Lourenco, SN; Teixeira, VS; Chimalapati, S; George, PJ; Janes, SM; Giangreco, A (Springer Nature, 2016-04-01)
      Although squamous cell carcinomas (SqCCs) of the lungs, head and neck, oesophagus, and cervix account for up to 30% of cancer deaths, the mechanisms that regulate disease progression remain incompletely understood. Here, ...

    • Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids. 

      Linch, M; Sanz-Garcia, M; Rosse, C; Riou, P; Peel, N; Madsen, CD; Sahai, E; Downward, J; Khwaja, A; Dillon, C (2014-02)
      Protein kinase C iota (PKCι), a serine/threonine kinase required for cell polarity, proliferation and migration, is commonly up- or downregulated in cancer. PKCι is a human oncogene but whether this is related to its role ...