Browsing Centre for Tumour Biology by Subject "Proteomics"

Now showing items 1-2 of 2

    • Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism. 

      Watts, ER; Howden, AJ; Morrison, T; Sadiku, P; Hukelmann, J; von Kriegsheim, A; Ghesquiere, B; Murphy, F; Mirchandani, AS; Humphries, DC (2021-05-17)
      Limiting dysfunctional neutrophilic inflammation while preserving effective immunity requires a better understanding of the processes that dictate neutrophil function in the tissues. Quantitative mass-spectrometry identified ...

    • Multifactorial Remodeling of the Cancer Immunopeptidome by IFNγ. 

      Newey, A; Yu, L; Barber, LJ; Choudhary, JS; Bassani-Sternberg, M; Gerlinger, M (American Association for Cancer Research, 2023-11-17)
      UNLABELLED: IFNγ alters the immunopeptidome presented on HLA class I (HLA-I), and its activity on cancer cells is known to be important for effective immunotherapy responses. We performed proteomic analyses of untreated ...