Browsing Centre for Tumour Biology by Subject "Protein Biosynthesis"

Now showing items 1-2 of 2

    • Alteration of ribosome function upon 5-fluorouracil treatment favors cancer cell drug-tolerance. 

      Therizols, G; Bash-Imam, Z; Panthu, B; Machon, C; Vincent, A; Ripoll, J; Nait-Slimane, S; Chalabi-Dchar, M; Gaucherot, A; Garcia, M (2022-01-10)
      Mechanisms of drug-tolerance remain poorly understood and have been linked to genomic but also to non-genomic processes. 5-fluorouracil (5-FU), the most widely used chemotherapy in oncology is associated with resistance. ...

    • Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism. 

      Watts, ER; Howden, AJ; Morrison, T; Sadiku, P; Hukelmann, J; von Kriegsheim, A; Ghesquiere, B; Murphy, F; Mirchandani, AS; Humphries, DC (2021-05-17)
      Limiting dysfunctional neutrophilic inflammation while preserving effective immunity requires a better understanding of the processes that dictate neutrophil function in the tissues. Quantitative mass-spectrometry identified ...