Browsing Centre for Tumour Biology by Subject "Disease Progression"

Now showing items 1-3 of 3

    • CADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity. 

      Vallath, S; Sage, EK; Kolluri, KK; Lourenco, SN; Teixeira, VS; Chimalapati, S; George, PJ; Janes, SM; Giangreco, A (Springer Nature, 2016-04-01)
      Although squamous cell carcinomas (SqCCs) of the lungs, head and neck, oesophagus, and cervix account for up to 30% of cancer deaths, the mechanisms that regulate disease progression remain incompletely understood. Here, ...

    • Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer. 

      Lote, H; Spiteri, I; Ermini, L; Vatsiou, A; Roy, A; McDonald, A; Maka, N; Balsitis, M; Bose, N; Simbolo, M (2017-06-01)
      BACKGROUND: Patients often ask oncologists how long a cancer has been present before causing symptoms or spreading to other organs. The evolutionary trajectory of cancers can be defined using phylogenetic approaches but ...

    • Insights Into the Pathophysiology of Esophageal Adenocarcinoma. 

      Quante, M; Graham, TA; Jansen, M (2018-01)
      Although researchers have identified genetic alterations that contribute to development of esophageal adenocarcinoma, we know little about features of patients or environmental factors that mediate progression of chronic ...