Browsing Centre for Tumour Biology by Author "East, JE"
Now showing items 1-3 of 3
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Evolutionary history of human colitis-associated colorectal cancer
Baker, A-M; Cross, W; Curtius, K; Al Bakir, I; Choi, C-HR; Davis, HL; Temko, D; Biswas, S; Martinez, P; Williams, MJ (2019-06) -
The evolutionary landscape of colorectal tumorigenesis
Cross, W; Kovac, M; Mustonen, V; Temko, D; Davis, H; Baker, A-M; Biswas, S; Arnold, R; Chegwidden, L; Gatenbee, C (2018-10)The evolutionary events that cause colorectal adenomas (benign) to progress to carcinomas (malignant) remain largely undetermined. Using multi-region genome and exome sequencing of 24 benign and malignant colorectal tumours, ... -
Multicentre derivation and validation of a colitis-associated colorectal cancer risk prediction web tool.
Curtius, K; Kabir, M; Al Bakir, I; Choi, CHR; Hartono, JL; Johnson, M; East, JE; Oxford IBD Cohort Study Investigators; Lindsay, JO; Vega, R (BMJ, 2021-05-14)OBJECTIVE: Patients with ulcerative colitis (UC) diagnosed with low-grade dysplasia (LGD) have increased risk of developing advanced neoplasia (AN: high-grade dysplasia or colorectal cancer). We aimed to develop and validate ...