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SET-PP2A complex as a new therapeutic target in KMT2A (MLL) rearranged AML.
(2023-10-27)
KMT2A-rearranged (KMT2A-R) is an aggressive and chemo-refractory acute leukemia which mostly affects children. Transcriptomics-based characterization and chemical interrogation identified kinases as key drivers of survival ...