Browsing Centre for Haemato-Oncology by Title

The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice

Langie, SAS; Cameron, KM; Ficz, G; Oxley, D; Tomaszewski, B; Gorniak, JP; Maas, LM; Godschalk, RWL; van Schooten, FJ; Reik, W (2017-02)

Autophagy mediates degradation of nuclear lamina

Dou, Z; Xu, C; Donahue, G; Shimi, T; Pan, J-A; Zhu, J; Ivanov, A; Capelll, BC; Drake, AM; Shah, PP (2015-11-05)

CD160 signaling mediates PI3K-dependent survival and growth signals in chronic lymphocytic leukemia

Liu, FT; Giustiniani, J; Farren, T; Jia, L; Bensussan, A; Gribben, JG; Agrawal, SG (2010-04-15)

The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia.

Di Tullio, A; Rouault-Pierre, K; Abarrategi, A; Mian, S; Grey, W; Gribben, J; Stewart, A; Blackwood, E; Bonnet, D (2017-11-22)

Cytarabine (AraC) represents the most effective single agent treatment for AML. Nevertheless, overriding AraC resistance in AML remains an unmet medical need. Here we show that the CHK1 inhibitor (CHK1i) GDC-0575 enhances ...

Current challenges in software solutions for mass spectrometry-based quantitative proteomics

Cappadona, S; Baker, PR; Cutillas, PR; Heck, AJR; van Breukelen, B (2012-09)

Development and validation of an ultra-high performance LC-MS/MS assay for intracellular SN-38 in human solid tumour cell lines: Comparison with a validated HPLC-fluorescence method

Ghazaly, E; Perry, J; Kitromilidou, C; Powles, T; Joel, S (2014-10-15)

Development of HPLC-UV method for rapid and sensitive analysis of topically applied tetracaine: its comparison with a CZE method

Al-Otaibi, F; Ghazaly, E; Johnston, A; Perrett, D (2014-06)

Diabetes-Related Autoantibodies in Children With Acute Lymphoblastic Leukemia

Bizzarri, C; Pinto, RM; Pitocco, D; Astorri, E; Cappa, M; Hawa, M; Giannone, G; Palermo, A; Maddaloni, E; Leslie, DRG (2012-03)

A distinct plasmablast and naive B-cell phenotype in primary immune thrombocytopenia

Flint, SM; Gibson, A; Lucas, G; Nandigam, R; Taylor, L; Provan, D; Newland, AC; Savage, CO; Henderson, RB (2016-06)

Disulfide-activated protein kinase G I alpha regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response

Scotcher, J; Prysyazhna, O; Boguslavskyi, A; Kistamas, K; Hadgraft, N; Martin, ED; Worthington, J; Rudyk, O; Cutillas, PR; Cuello, F (2016-10-26)

Durable graft-versus-leukaemia effects without donor lymphocyte infusions - results of a phase II study of sequential T-replete allogeneic transplantation for high-risk acute myeloid leukaemia and myelodysplasia.

Davies, JK; Hassan, S; Sarker, S-J; Besley, C; Oakervee, H; Smith, M; Taussig, D; Gribben, JG; Cavenagh, JD (2018-02)

Allogeneic haematopoietic stem-cell transplantation remains the only curative treatment for relapsed/refractory acute myeloid leukaemia (AML) and high-risk myelodysplasia but has previously been limited to patients who ...

Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis

Wang, P; Wang, P; Liu, B; Zhao, J; Pang, Q; Agrawal, SG; Jia, L; Liu, F-T (2015-09-08)

Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors

Horton, SJ; Giotopoulos, G; Yun, H; Vohra, S; Sheppard, O; Bashford-Rogers, R; Rashid, M; Clipson, A; Chan, W-I; Sasca, D (2017-09)

ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients

Tissot, F; Agrawal, S; Pagano, L; Petrikkos, G; Groll, AH; Skiada, A; Lass-Floerl, C; Calandra, T; Viscoli, C; Herbrecht, R (2017-03)