Browsing Centre for Haemato-Oncology by Title

THE ADDITION OF RITUXIMAB TO CODOX-M/IVAC CHEMOTHERAPY IN THE TREATMENT OF BURKITT LYMPHOMA IS SAFE AND IS ASSOCIATED WITH INCREASED EFFICACY IN THE HIV POSITIVE POPULATION

Alwan, F; He, A; Montoto, S; Kassam, S; Mee, M; Burns, F; Edwards, S; Wilson, A; Tenant-Flowers, M; Marcus, R (2014-06-01)

The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice

Langie, SAS; Cameron, KM; Ficz, G; Oxley, D; Tomaszewski, B; Gorniak, JP; Maas, LM; Godschalk, RWL; van Schooten, FJ; Reik, W (2017-02)

Alternative donors extend transplantation for patients with lymphoma who lack an HLA matched donor

Bachanova, V; Burns, LJ; Wang, T; Carreras, J; Gale, RP; Wiernik, PH; Ballen, KK; Wirk, B; Munker, R; Rizzieri, DA (2015-02)

Augmenting Autologous Stem Cell Transplantation to Improve Outcomes in Myeloma

Maybury, B; Cook, G; Pratt, G; Yong, K; Ramasamy, K (2016-11)

Autophagy mediates degradation of nuclear lamina

Dou, Z; Xu, C; Donahue, G; Shimi, T; Pan, J-A; Zhu, J; Ivanov, A; Capelll, BC; Drake, AM; Shah, PP (2015-11-05)

BIM mediates synergistic killing of B-cell acute lymphoblastic leukemia cells by BCL-2 and MEK inhibitors

Korfi, K; Smith, M; Swan, J; Somervaille, TCP; Dhomen, N; Marais, R (2016-04)

Blocking Autophagy Prevents Bortezomib-Induced NF-kappa B Activation by Reducing I-kappa B alpha Degradation in Lymphoma Cells

Jia, L; Gopinathan, G; Sukumar, JT; Gribben, JG (2012-02-29)

CD160 signaling mediates PI3K-dependent survival and growth signals in chronic lymphocytic leukemia

Liu, FT; Giustiniani, J; Farren, T; Jia, L; Bensussan, A; Gribben, JG; Agrawal, SG (2010-04-15)

Chloroquine targets pancreatic cancer stem cells via inhibition of CXCR4 and hedgehog signaling.

Balic, A; Sørensen, MD; Trabulo, SM; Sainz, B; Cioffi, M; Vieira, CR; Miranda-Lorenzo, I; Hidalgo, M; Kleeff, J; Erkan, M (2014-07)

Pancreatic ductal adenocarcinoma is one of the deadliest carcinomas and is characterized by highly tumorigenic and metastatic cancer stem cells (CSC). CSCs evade available therapies, which preferentially target highly ...

CLOFARABINE IN COMBINATION WITH HIGH-DOSE CYTARABINE AND LIPOSOMAL DAUNORUBICIN IN PEDIATRIC AML: RESULTS OF A PHASE 1 COMBINATION STUDY BY THE ITCC CONSORTIUM

Zwaan, CM; Dworzak, M; Klingebiel, T; Roessig, C; Leverger, G; Stary, J; de Bont, ES; Niemeyer, CM; Kaspers, GJ; Bertrand, Y (2014-12)

The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia.

Di Tullio, A; Rouault-Pierre, K; Abarrategi, A; Mian, S; Grey, W; Gribben, J; Stewart, A; Blackwood, E; Bonnet, D (2017-11-22)

Cytarabine (AraC) represents the most effective single agent treatment for AML. Nevertheless, overriding AraC resistance in AML remains an unmet medical need. Here we show that the CHK1 inhibitor (CHK1i) GDC-0575 enhances ...

Current challenges in software solutions for mass spectrometry-based quantitative proteomics

Cappadona, S; Baker, PR; Cutillas, PR; Heck, AJR; van Breukelen, B (2012-09)

Dangerous power: mitochondria in CLL cells.

JIA, L; Gribben, GJ (American Society of Hematology, 2014-04-24)

Development and validation of an ultra-high performance LC-MS/MS assay for intracellular SN-38 in human solid tumour cell lines: Comparison with a validated HPLC-fluorescence method

Ghazaly, E; Perry, J; Kitromilidou, C; Powles, T; Joel, S (2014-10-15)

Development of HPLC-UV method for rapid and sensitive analysis of topically applied tetracaine: its comparison with a CZE method

Al-Otaibi, F; Ghazaly, E; Johnston, A; Perrett, D (2014-06)

Diabetes-Related Autoantibodies in Children With Acute Lymphoblastic Leukemia

Bizzarri, C; Pinto, RM; Pitocco, D; Astorri, E; Cappa, M; Hawa, M; Giannone, G; Palermo, A; Maddaloni, E; Leslie, DRG (2012-03)

A distinct plasmablast and naive B-cell phenotype in primary immune thrombocytopenia

Flint, SM; Gibson, A; Lucas, G; Nandigam, R; Taylor, L; Provan, D; Newland, AC; Savage, CO; Henderson, RB (2016-06)

Disulfide-activated protein kinase G I alpha regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response

Scotcher, J; Prysyazhna, O; Boguslavskyi, A; Kistamas, K; Hadgraft, N; Martin, ED; Worthington, J; Rudyk, O; Cutillas, PR; Cuello, F (2016-10-26)

Durable graft-versus-leukaemia effects without donor lymphocyte infusions - results of a phase II study of sequential T-replete allogeneic transplantation for high-risk acute myeloid leukaemia and myelodysplasia.

Davies, JK; Hassan, S; Sarker, S-J; Besley, C; Oakervee, H; Smith, M; Taussig, D; Gribben, JG; Cavenagh, JD (2018-02)

Allogeneic haematopoietic stem-cell transplantation remains the only curative treatment for relapsed/refractory acute myeloid leukaemia (AML) and high-risk myelodysplasia but has previously been limited to patients who ...

Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis

Wang, P; Wang, P; Liu, B; Zhao, J; Pang, Q; Agrawal, SG; Jia, L; Liu, F-T (2015-09-08)