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Surgical decision making in premenopausal BRCA carriers considering risk reducing early-salpingectomy or salpingo-oophorectomy: a Qualitative Study
Background: Acceptance of the role of the fallopian tube in “ovarian” carcinogenesis and the detrimental sequelae of surgical menopause in pre-menopausal women following risk-reducing-salpingo-oophorectomy (RRSO), has ...
Population Based Testing for Primary Prevention: A Systematic Review
(2018-09-30)
The current clinical model for genetic-testing is based on clinical-criteria/family-history(FH) and a pre-defined mutation probability threshold. It requires people to develop cancer before identifying unaffected ...