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This article has been accepted for publication in Journal of Medical Genetics, 2018 following peer review, and the Version of Record can be accessed online at http://dx.doi.org/10.1136/jmedgenet-2017-105195. © 2018. Reuse of this manuscript version is permitted strictly pursuant to the terms of the CC-BY-NC-ND 4.0 license: http://creativecommons.org/licenses/by-nc-nd/4.0/
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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.