Browsing Barts Cancer Institute by Title
Now showing items 1094-1113 of 1149
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TP53 outperforms other androgen receptor biomarkers to predict abiraterone or enzalutamide outcome in metastatic castration-resistant prostate cancer.
(2018-09-12)PURPOSE: To infer the prognostic value of simultaneous androgen receptor (AR) and TP53 profiling in liquid biopsies from metastatic castration-resistant prostate cancer (mCRPC) patients starting a new line of AR signalling ... -
The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes.
(2023-09)Most cancer types exhibit aberrant transcriptional activity, including derepression of retrotransposable elements (RTEs). However, the degree, specificity and potential consequences of RTE transcriptional activation may ... -
Transcriptional profiling identifies differential expression of long non-coding RNAs in Jo-1 associated and inclusion body myositis.
(2017-08-14)Myositis is characterised by muscle inflammation and weakness. Although generally thought to be driven by a systemic autoimmune response, increasing evidence suggests that intrinsic changes in the muscle might also contribute ... -
A Transcriptomic Comparison of Two Bambara Groundnut Landraces under Dehydration Stress
(MDPI, 2017-04-18)The ability to grow crops under low-water conditions is a significant advantage in relation to global food security. Bambara groundnut is an underutilised crop grown by subsistence farmers in Africa and is known to survive ... -
Transition state characteristics during cell differentiation
(Public Library of Science, 2018-09-20)Models describing the process of stem-cell differentiation are plentiful, and may offer insights into the underlying mechanisms and experimentally observed behaviour. Waddington’s epigenetic landscape has been providing a ... -
Tumour associated macrophage recruitment in SCC
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Tumour Cell Heterogeneity.
(2016)The population of cells that make up a cancer are manifestly heterogeneous at the genetic, epigenetic, and phenotypic levels. In this mini-review, we summarise the extent of intra-tumour heterogeneity (ITH) across human ...