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    Tumour Cell Heterogeneity. 
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    Tumour Cell Heterogeneity.

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    Published version (2.340Mb)
    Volume
    5
    DOI
    10.12688/f1000research.7210.1
    Journal
    F1000Res
    ISSN
    2046-1402
    Metadata
    Show full item record
    Abstract
    The population of cells that make up a cancer are manifestly heterogeneous at the genetic, epigenetic, and phenotypic levels. In this mini-review, we summarise the extent of intra-tumour heterogeneity (ITH) across human malignancies, review the mechanisms that are responsible for generating and maintaining ITH, and discuss the ramifications and opportunities that ITH presents for cancer prognostication and treatment.
    Authors
    Gay, L; Baker, A-M; Graham, TA
    URI
    http://qmro.qmul.ac.uk/xmlui/handle/123456789/15126
    Collections
    • Centre for Tumour Biology [301]
    Language
    eng
    Licence information
    CC-BY
    Copyright statements
    © 2016 Gay L et al.
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