Browsing Barts Cancer Institute by Title
Now showing items 1077-1096 of 1165
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T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice.
(2015-11)Chronic lymphocytic leukaemia (CLL) cells require microenvironmental support for their proliferation. This can be recapitulated in highly immunocompromised hosts in the presence of T cells and other supporting cells. Current ... -
Targeting CDH17 in Cancer: When Blocking the Ligand Beats Blocking the Receptor?
(2018-01-15)Cadherin-17 (CDH17) has been implicated as protumorigenic for many years, but mechanisms have been unclear. A Spanish team has generated antibodies to an RGD motif in CDH17 that inhibits integrin α2β1 binding to CDH17 and ... -
Targeting FGFR signalling to disrupt cellular cross-talk in pancreatic cancer
(Elsevier, 2020-12-01) -
Targeting inflammatory cytokines in cancer
(2014-11) -
Targeting Versican as a Potential Immunotherapeutic Strategy in the Treatment of Cancer.
(2021)A growing body of literature links events associated with the progression and severity of immunity and inflammatory disease with the composition of the tissue extracellular matrix as defined by the matrisome. One protein ...