Browsing Barts Cancer Institute by Title
Now showing items 203-222 of 1159
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Critical questions in ovarian cancer research and treatment: Report of an American Association for Cancer Research Special Conference.
(2019-06-15)Substantial progress has been made in understanding ovarian cancer at the molecular and cellular level. Significant improvement in 5-year survival has been achieved through cytoreductive surgery, combination platinum-based ... -
Crypt fusion as a homeostatic mechanism in the human colon.
(BMJ, 2019-03-14)OBJECTIVE: The crypt population in the human intestine is dynamic: crypts can divide to produce two new daughter crypts through a process termed crypt fission, but whether this is balanced by a second process to remove ... -
CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma
(American Association for Cancer Research, 2016-06-20)Other than an association with HPV infection, little is known about the genetic alterations determining the development of penile cancer. Although penile cancer is rare in the developed world, it presents a significant ... -
Cumulative burden of inflammation predicts colorectal neoplasia risk in ulcerative colitis: a large single-centre study.
(2017-11-17)OBJECTIVE: Ulcerative colitis (UC) is a dynamic disease with its severity continuously changing over time. We hypothesised that the risk of colorectal neoplasia (CRN) in UC closely follows an actuarial accumulative ... -
Current Perspectives on the Use of off the Shelf CAR-T/NK Cells for the Treatment of Cancer
(MDPI, 2021-04)CAR T cells have revolutionised the treatment of haematological malignancies. Despite this, several obstacles still prohibit their widespread use and efficacy. One of these barriers is the use of autologous T cells as ...