Browsing Mathematics by Subject "Humans"
Now showing items 1-15 of 15
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Diffusion segregation and the disproportionate incidence of COVID-19 in African American communities.
(The Royal Society Publishing, 2021-01)One of the most concerning aspects of the ongoing COVID-19 pandemic is that it disproportionately affects people from some specific ethnic and socio-economic minorities. In particular, since from the beginning of the ... -
Estimating the most efficient allocation of interventions to achieve reductions in Plasmodium falciparum malaria burden and transmission in Africa: a modelling study.
(2016-07)BACKGROUND: Reducing the burden of malaria is a global priority, but financial constraints mean that available resources must be allocated rationally to maximise their effect. We aimed to develop a model to estimate the ... -
A flexible method for optimising sharing of healthcare resources and demand in the context of the COVID-19 pandemic.
(PLoS, 2020)As the number of cases of COVID-19 continues to grow, local health services are at risk of being overwhelmed with patients requiring intensive care. We develop and implement an algorithm to provide optimal re-routing ... -
The impact of pyrethroid resistance on the efficacy and effectiveness of bednets for malaria control in Africa.
(2016-08-22)Long lasting pyrethroid treated bednets are the most important tool for preventing malaria. Pyrethroid resistant Anopheline mosquitoes are now ubiquitous in Africa, though the public health impact remains unclear, impeding ... -
The interaction between seasonality and pulsed interventions against malaria in their effects on the reproduction number.
(2015-01)The basic reproduction number (R0) is an important quantity summarising the dynamics of an infectious disease, as it quantifies how much effort is needed to control transmission. The relative change in R0 due to an ... -
LSTM-CNN: An efficient diagnostic network for Parkinson's disease utilizing dynamic handwriting analysis.
(2024-04)BACKGROUND AND OBJECTIVES: Dynamic handwriting analysis, due to its noninvasive and readily accessible nature, has emerged as a vital adjunctive method for the early diagnosis of Parkinson's disease (PD). An essential step ... -
Modelling collinear and spatially correlated data.
(2016-08)In this work we present a statistical approach to distinguish and interpret the complex relationship between several predictors and a response variable at the small area level, in the presence of (i) high correlation between ... -
Modelling population-level impact to inform target product profiles for childhood malaria vaccines.
(2018-07-13)BACKGROUND: The RTS,S/AS01 vaccine for Plasmodium falciparum malaria demonstrated moderate efficacy in 5-17-month-old children in phase 3 trials, and from 2018, the vaccine will be evaluated through a large-scale pilot ... -
Motor-commands decoding using peripheral nerve signals: a review.
(2018-06)During the last few decades, substantial scientific and technological efforts have been focused on the development of neuroprostheses. The major emphasis has been on techniques for connecting the human nervous system with ... -
Neuroscience Needs Network Science.
(The Society for Neuroscience, 2023-08-23)The brain is a complex system comprising a myriad of interacting neurons, posing significant challenges in understanding its structure, function, and dynamics. Network science has emerged as a powerful tool for studying ... -
Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts.
(2017-01)Over a century since Ronald Ross discovered that malaria is caused by the bite of an infectious mosquito it is still unclear how the number of parasites injected influences disease transmission. Currently it is assumed ... -
Rapid, large-scale, and effective detection of COVID-19 via non-adaptive testing.
(2020-12-07)Pooling of samples can increase lab capacity when using Polymerase chain reaction (PCR) to detect diseases such as COVID-19. However, pool testing is typically performed via an adaptive testing strategy which requires a ... -
Role of the central cations in the mechanical unfolding of DNA and RNA G-quadruplexes.
(2015-09-03)Cations are known to mediate diverse interactions in nucleic acids duplexes but they are critical in the arrangement of four-stranded structures. Here, we use all-atom molecular dynamics simulations with explicit solvent ... -
Stochastic game dynamics under demographic fluctuations.
(2015-07-21)Frequency-dependent selection and demographic fluctuations play important roles in evolutionary and ecological processes. Under frequency-dependent selection, the average fitness of the population may increase or decrease ... -
A Topological Criterion for Filtering Information in Complex Brain Networks.
(2017-01)In many biological systems, the network of interactions between the elements can only be inferred from experimental measurements. In neuroscience, non-invasive imaging tools are extensively used to derive either structural ...