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Pro-migratory and TGF-beta-activating functions of alpha v beta 6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch

dc.contributor.authorTod, Jen_US
dc.contributor.authorHanley, CJen_US
dc.contributor.authorMorgan, MRen_US
dc.contributor.authorRucka, Men_US
dc.contributor.authorMellows, Ten_US
dc.contributor.authorLopez, M-Aen_US
dc.contributor.authorKiely, Pen_US
dc.contributor.authorMoutasim, KAen_US
dc.contributor.authorFrampton, SJen_US
dc.contributor.authorSabnis, Den_US
dc.contributor.authorFine, DRen_US
dc.contributor.authorJohnson, Cen_US
dc.contributor.authorMarshall, JFen_US
dc.contributor.authorScita, Gen_US
dc.contributor.authorJenei, Ven_US
dc.contributor.authorThomas, GJen_US
dc.date.accessioned2018-02-23T15:25:25Z
dc.date.available2017-05-24en_US
dc.date.issued2017-09en_US
dc.date.submitted2018-02-22T10:43:40.789Z
dc.identifier.issn0022-3417en_US
dc.identifier.other10.1002/path.4923
dc.identifier.urihttp://onlinelibrary.wiley.com/wol1/doi/10.1002/path.4923/abstract
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/33525
dc.description.sponsorshipThis work was funded by the MedicalResearch Council (Grant No G1002008; JT) and Can-cer Research UK (Grant No C11512/A20256; GJT).JT was also supported by a Pancreatic Cancer UKFuture Research Leaders Fund Award and a PancreaticCancer UK and Freemasons’ Grand Charity MedicalResearch Grant. VJ was supported by two Wessex Med-ical Research Innovation Grantsen_US
dc.format.extent37 - 50en_US
dc.language.isoenen_US
dc.relation.ispartofJOURNAL OF PATHOLOGYen_US
dc.rightsCreative Commons Attribution License
dc.subjectalpha v beta 6en_US
dc.subjectEps8en_US
dc.subjectTGF-beta 1en_US
dc.subjectmotilityen_US
dc.subjectRac1en_US
dc.subjectRhoen_US
dc.titlePro-migratory and TGF-beta-activating functions of alpha v beta 6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switchen_US
dc.typeArticle
dc.rights.holder2017 The Authors.
dc.identifier.doi10.1002/path.4923en_US
pubs.author-urlhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000407897500005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=612ae0d773dcbdba3046f6df545e9f6aen_US
pubs.issue1en_US
pubs.notesNo embargoen_US
pubs.publication-statusPublisheden_US
pubs.volume243en_US


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