Browsing Centre for Cancer Prevention by Subject "Cell Transformation, Neoplastic"

Now showing items 1-2 of 2

    • Clone competition as a mechanism to reduce tumor formation. 

      Acha-Sagredo, A; Malanchi, I; Ciccarelli, FD (2021-12-20)
      With age, clones carrying somatic mutations in well-known cancer driver genes progressively populate adult tissues, yet cancer transformation is rare. In a recent issue of Nature, Colom et al. showed that competition between ...

    • Lung adenocarcinoma promotion by air pollutants. 

      Hill, W; Lim, EL; Weeden, CE; Lee, C; Augustine, M; Chen, K; Kuan, F-C; Marongiu, F; Evans, EJ; Moore, DA (Nature, 2023-04-05)
      A complete understanding of how exposure to environmental substances promotes cancer formation is lacking. More than 70 years ago, tumorigenesis was proposed to occur in a two-step process: an initiating step that induces ...