Browsing Centre for Translational Medicine & Therapeutics by Subject "ibrutinib"
Now showing items 1-3 of 3
-
X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure
(Frontiers Media, 2020-10-07)We previously reported the Bruton's tyrosine kinase (BTK) inhibitors ibrutinib and acalabrutinib improve outcomes in a mouse model of polymicrobial sepsis. Now we show that genetic deficiency of the BTK gene alone in Xid ...