Browsing Centre for Translational Medicine & Therapeutics by Subject "Base Sequence"
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A functional screen for regulators of CKDN2A reveals MEOX2 as a transcriptional activator of INK4a.
(Public Library of Science, 2009-04-02)The CDKN2A locus encodes two important tumor suppressors, INK4a and ARF, which respond to oncogenic stresses by inducing cellular senescence. We conducted a genome-scale cDNA overexpression screen using a reporter containing ...