Browsing Centre for Translational Medicine & Therapeutics by Subject "2-hydroxygluterate dehydrogenase"
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2-Hydroxyglutarate Metabolism Is Altered in an in vivo Model of LPS Induced Endotoxemia.
(Frontiers Media, 2020-03-03)The metabolic response to endotoxemia closely mimics those seen in sepsis. Here, we show that the urinary excretion of the metabolite 2-hydroxyglutarate (2HG) is dramatically suppressed following lipopolysaccharide (LPS) ...