Browsing Centre for Translational Medicine & Therapeutics by Author "Wan, YI"
Now showing items 1-20 of 23
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Acute Kidney Injury in COVID-19: multicentre prospective analysis of registry data
Wan, YI; Bien, Z; Apea, VJ; Orkin, CM; Dhairyawan, R; Kirwan, CJ; Pearse, RM; Puthucheary, ZA; Prowle, JR (2021-03-27) -
Association between calorie surplus and ICU length of stay in the critically ill: A retrospective cohort study.
Page, A; Langan, A; Wan, YI; McNelly, A; Prowle, J; Pearse, R; Puthucheary, Z (2023-12-04)BACKGROUND & AIMS: Patients suffering persistent critical illness have poor short and long-term outcomes and consume disproportionate amounts of heath care resources. Nutritional optimisation may improve outcomes, though ... -
Catabolism in Critical Illness: A Reanalysis of the REducing Deaths due to OXidative Stress (REDOXS) Trial*
Haines, RW; Fowler, AJ; Wan, YI; Flower, L; Heyland, DK; Day, A; Pearse, RM; Prowle, JR; Puthucheary, Z (2022) -
Characterising biological mechanisms underlying ethnicity-associated outcomes in COVID-19 through biomarker trajectories: a multicentre registry analysis.
Wan, YI; Puthucheary, ZA; Pearse, RM; Prowle, JR (2023-09)BACKGROUND: Differences in routinely collected biomarkers between ethnic groups could reflect dysregulated host responses to disease and to treatments, and be associated with excess morbidity and mortality in COVID-19. ... -
Characteristics and Outcomes of Patients With Frailty Admitted to ICU With Coronavirus Disease 2019: An Individual Patient Data Meta-Analysis.
Subramaniam, A; Anstey, C; Curtis, JR; Ashwin, S; Ponnapa Reddy, M; Aliberti, MJR; Avelino-Silva, TJ; Welch, C; Koduri, G; Prowle, JR (2022-01)UNLABELLED: Frailty is often used in clinical decision-making for patients with coronavirus disease 2019, yet studies have found a variable influence of frailty on outcomes in those admitted to the ICU. In this individual ... -
COVID-19 Phenotypes and Potential Harm of Conventional Treatments: How to Prove the Hypothesis
Fowler, AJ; Wan, YI; Carenzo, L; Haines, RW (American Thoracic Society, 2020-08-15) -
Critical care and pandemic preparedness and response.
Thomson, WR; Puthucheary, ZA; Wan, YI (2023-09-07)Critical care was established partially in response to a polio epidemic in the 1950s. In the intervening 70 yr, several epidemics and pandemics have placed critical care and allied services under extreme pressure. Pandemics ... -
Dynamic dosing for continuous renal replacement therapy: Service evaluation of the safety and effectiveness of titrating dose to biochemistry
Eldridge, JC; Shah, AB; Lucena-Amaro, S; Kirwan, CJ; Prowle, JR; Wan, YI (2023) -
ETHICAL: Ethnic Disparities In COVID-19 Admissions in east London
Wan, YI; Apea, V; Dhairyawan, R; Orkin, C; Pearse, RM; Prowle, JR (Queen Mary University of London, Critical Care and Preoperative Medicine Research Group, 2020-05-18)This study aims to assess whether there is a difference in age and sex adjusted outcomes in different ethnicities of patients with confirmed COVID 19 admitted to Barts Health. The study will test the hypothesis that there ... -
Ethnic disparities in hospitalisation and hospital-outcomes during the second wave of COVID-19 infection in east London
Wan, YI; Apea, VJ; Dhairyawan, R; Puthucheary, ZA; Pearse, RM; Orkin, CM; Prowle, JR (2021-07-07)This article is a preprint and has not been peer-reviewed. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice. ABSTRACT Objectives To determine if changes ... -
Ethnicity and acute hospital admissions: Multi-center analysis of routine hospital data
Wan, YI; Robbins, AJ; Apea, VJ; Orkin, CM; Pearse, R; Puthucheary, ZA; Prowle, JR (2021-08-19)Background: The effects of ethnic and social inequalities on patient outcomes in acute healthcare remain poorly understood. Methods: Prospectively-defined analysis of registry data from four acute NHS hospitals in east ... -
Ethnicity and outcomes in patients hospitalised with COVID-19 infection in East London: an observational cohort study.
Apea, VJ; Wan, YI; Dhairyawan, R; Puthucheary, ZA; Pearse, RM; Orkin, CM; Prowle, JR (BMJ, 2021-01-17)OBJECTIVE: To describe outcomes within different ethnic groups of a cohort of hospitalised patients with confirmed COVID-19 infection. To quantify and describe the impact of a number of prognostic factors, including frailty ... -
Health Resource Utilisation and Disparities: an Ecological Study of Admission Patterns Across Ethnicity in England Between 2017 and 2020
Toal, CM; Fowler, AJ; Pearse, RM; Puthucheary, Z; Prowle, JR; Wan, YI (2022) -
Hemoperfusion in Trauma.
Eldridge, JC; Wan, YI; Prowle, JR (2023)Major trauma care has seen significant improvements in early mortality, reflecting improvements in prehospital techniques for hemorrhage control and speed of access to specialized trauma centers. However, many patients ... -
Liberal or restrictive antimicrobial prophylaxis for surgical site infection: systematic review and meta-analysis of randomised trials
Fowler, AJ; Dias, P; Hui, S; Cashmore, R; Laloo, R; Ahmad, AN; Gillies, MA; Wan, YI; Pearse, RM; Abbott, TEF (2022) -
Long-term mortality following complications after elective surgery a secondary analysis of pooled data from two prospective cohort studies
Fowler, AJ; Wan, YI; Prowle, JR; Chew, M; Campbell, D; Cuthbertson, B; Wijeysundera, DN; Pearse, R; Abbott, T (2022) -
Patient monitoring, wearable devices, and the healthcare information ecosystem
Webster, CS; Scheeren, TWL; Wan, YI (2022) -
Postoperative infection and mortality following elective surgery in the International Surgical Outcomes Study (ISOS)
Wan, YI; Patel, A; Achary, C; Hewson, R; Phull, M; Pearse, RM (2021) -
Prognostic association of routinely measured biomarkers in patients admitted to critical care: a systematic review.
Wan, YI; Brayne, AB; Haines, RW; Puthucheary, ZA; Prowle, JR (2020-11-05)PURPOSE: To examine reported prognostic associations of routine blood measurements in the intensive care unit. MATERIALS AND METHODS: We searched PubMed, EMBASE through 28th May 2020 to identify all studies in adult critical ... -
Resource requirements for reintroducing elective surgery during the COVID-19 pandemic: modelling study
Fowler, AJ; Dobbs, TD; Wan, YI; Laloo, R; Hui, S; Nepogodiev, D; Bhangu, A; Whitaker, IS; Pearse, RM; Abbott, TEF (2020-12-21)