Browsing Centre for Translational Medicine & Therapeutics by Author "Hadjihambi, A"
Now showing items 1-4 of 4
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Adenosine signalling to astrocytes coordinates brain metabolism and function.
Theparambil, SM; Kopach, O; Braga, A; Nizari, S; Hosford, PS; Sagi-Kiss, V; Hadjihambi, A; Konstantinou, C; Esteras, N; Gutierrez Del Arroyo, A (2024-07-03)Brain computation performed by billions of nerve cells relies on a sufficient and uninterrupted nutrient and oxygen supply1,2. Astrocytes, the ubiquitous glial neighbours of neurons, govern brain glucose uptake and ... -
Astrocytes produce nitric oxide via nitrite reduction in mitochondria to regulate cerebral blood flow during brain hypoxia.
Christie, IN; Theparambil, SM; Braga, A; Doronin, M; Hosford, PS; Brazhe, A; Mascarenhas, A; Nizari, S; Hadjihambi, A; Wells, JA (2023-11-30)During hypoxia, increases in cerebral blood flow maintain brain oxygen delivery. Here, we describe a mechanism of brain oxygen sensing that mediates the dilation of intraparenchymal cerebral blood vessels in response to ... -
The effect of general anaesthetics on brain lactate release
Hadjihambi, A; Karagiannis, A; Theparambil, SM; Ackland, GL; Gourine, AV (2020) -
NMDA receptor modulation of glutamate release in activated neutrophils
del Arroyo, AG; Hadjihambi, A; Sanchez, J; Turovsky, E; Kasymov, V; Cain, D; Nightingale, TD; Lambden, S; Grant, SGN; Gourine, AV (2019-09)