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Tuning the endothelial response: differential release of exocytic cargos from Weibel-Palade Bodies.
(Wiley, 2018-06-28)
BACKGROUND:
Endothelial cells harbour specialised storage organelles, Weibel-Palade Bodies (WPBs). Exocytosis of WPB content into the vascular lumen initiates primary haemostasis, mediated by Von Willebrands factor (VWF) ...
Tuning the endothelial response: differential release of exocytic cargos from Weibel-Palade bodies.
(2018-09)
Essentials Endothelial activation initiates multiple processes, including hemostasis and inflammation. The molecules that contribute to these processes are co-stored in secretory granules. How can the cells control release ...