Browsing Centre for Microvascular Research (CMR) by Subject "Acute Myeloid Leukemia"
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CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity.
(Ferrata Storti Foundation, 2020-07-02)Adhesive properties of leukemia cells shape the degree of organ infiltration and the extent of leukocytosis. CD44 and the integrin VLA-4, a CD49d/CD29 heterodimer, are important factors of progenitor cell adhesion in bone ...